We explored the relationship between vitamin E and heart attack risk through a two-sample mendelian randomization study. Using genetic variations from nearly 8,000 individuals of European descent, we dug into whether higher levels of vitamin E could protect against coronary artery disease (CAD) and myocardial infarction (MI).
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
Read More
9
VEGFA, bFGF enhance heart recovery
Enhanced human adipose-derived stem cells with VEGFA and bFGF mRNA promote stable vascular regeneration and improve cardiac function following myocardial infarction.
We aimed to uncover how the proteins VEGFA and bFGF can support heart recovery following a heart attack, and we did this by enhancing human adipose-derived stem cells (hADSCs) with modified mRNA. These proteins are known to play a role in improving blood flow and reducing cell death, both vital for effective healing.
By modifying the hADSCs to overexpress these proteins, we sought to improve their ability to support the heart during such a critical time. Importantly, our approach involved using a new technique that enables the hADSCs to produce these growth factors in a timed, efficient manner. This modification not only led to better survival of the transplanted cells but also promoted stable formation of new blood vessels at the site of injury.
We observed that the infused hADSCs improved overall heart function and electrical activity, suggesting a robust response to the proteins we introduced. The results indicate that the combination of these engineered stem cells and the proteins could substantially enhance recovery after a heart attack, paving the way for new treatments for heart diseases caused by ischemia.
Read More
9
Vitamin E reduces heart risks
Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype.
We examined how vitamin E affects individuals with diabetes and the specific Haptoglobin 2-2 genotype, who are at greater risk for heart problems. By analyzing data from two trials, we found that taking vitamin E significantly reduced the risk of heart events like strokes and heart attacks in these patients.
The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
Read More
Most Useful Reviews
9
Moisturises heart
Mrahha, it deeply moisturises the heart.
Read More
9
Nutrient-rich oil
1 people found this helpful
The quality of heavy wheat germ oil is exceptional, offering numerous health benefits. Mixing it with salad masks its flavour, making it enjoyable. It’s rich in 100% vitamin E and Omega 3, vital for heart health, hair, and more. Don’t overlook this product if you're focused on hair health!
Read More
7
Enhances cardiovascular health
1 people found this helpful
Delicious oil! It is of superb quality. While I can't drink it straight, I add it to my salad for its rich aroma, which enhances the flavour! This oil is packed with Omega and nutritious ingredients, improving bodily functions. It normalises heart activity and addresses inflammation. I've noticed my hair is now shinier and more vibrant! I highly recommend it. ❤️
We explored the potential of TAPI-1, a protein that inhibits harmful enzymes, in treating heart damage after a heart attack, using a novel delivery method. To enhance its effectiveness, researchers created nanoparticles that mimic neutrophils, a type of immune cell that quickly appears in injured heart tissue.
These specialized nanoparticles were loaded with TAPI-1 and specifically designed to target inflamed areas of the heart in rats following a heart attack. By delivering TAPI-1 more precisely, we aimed to reduce heart injury and improve heart function.
Our results were promising—injecting TAPI-1 through these neutrophil-mimicking nanoparticles led to better heart performance and less scar tissue compared to standard TAPI-1 treatments. Not only did the targeted approach seem to optimize the protein's effects, but it also helped lessen the overall inflammation within the heart.
In summary, this study highlights a strategic advancement in delivering the TAPI-1 protein that could lead to more effective treatments for heart attack recovery, ultimately improving patient outcomes.
Read More
9
VEGFA, bFGF enhance heart recovery
Enhanced human adipose-derived stem cells with VEGFA and bFGF mRNA promote stable vascular regeneration and improve cardiac function following myocardial infarction.
We aimed to uncover how the proteins VEGFA and bFGF can support heart recovery following a heart attack, and we did this by enhancing human adipose-derived stem cells (hADSCs) with modified mRNA. These proteins are known to play a role in improving blood flow and reducing cell death, both vital for effective healing.
By modifying the hADSCs to overexpress these proteins, we sought to improve their ability to support the heart during such a critical time. Importantly, our approach involved using a new technique that enables the hADSCs to produce these growth factors in a timed, efficient manner. This modification not only led to better survival of the transplanted cells but also promoted stable formation of new blood vessels at the site of injury.
We observed that the infused hADSCs improved overall heart function and electrical activity, suggesting a robust response to the proteins we introduced. The results indicate that the combination of these engineered stem cells and the proteins could substantially enhance recovery after a heart attack, paving the way for new treatments for heart diseases caused by ischemia.
Read More
9
Hydrogel with vitamin E aids recovery
Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair.
We explored how an innovative hydrogel enhanced heart repair after a heart attack. This injectable hydrogel includes α-tocopherol, a form of vitamin E. In our study using a rabbit model, we implanted the hydrogel after inducing a heart attack.
Four weeks later, the results were promising. We noticed improved heart function and reduced damage to heart tissue. This suggests that the hydrogel, enriched with vitamin E, plays a vital role in helping the heart recover better after an injury.
Read More
9
β-Cryptoxanthin outperforming vitamin E
β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice.
We investigated how three antioxidant compounds—β-cryptoxanthin, astaxanthin, and vitamin E—affect heart damage from ischemia-reperfusion injury in mice.
Mice were treated with these compounds before inducing heart injury.
Results showed that all treatments reduced heart damage, but β-cryptoxanthin was the most effective, shrinking heart injury by 60% compared to vitamin E and astaxanthin.
Ultimately, while vitamin E showed some benefits, β-cryptoxanthin stood out in reducing oxidative stress and cellular damage more effectively.
Read More
9
Vitamin E reduces heart risks
Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype.
We examined how vitamin E affects individuals with diabetes and the specific Haptoglobin 2-2 genotype, who are at greater risk for heart problems. By analyzing data from two trials, we found that taking vitamin E significantly reduced the risk of heart events like strokes and heart attacks in these patients.
The study suggests that screening diabetics for the Haptoglobin genotype and offering vitamin E as treatment could improve heart health and even extend life expectancy by three years for those affected.
The quality of heavy wheat germ oil is exceptional, offering numerous health benefits. Mixing it with salad masks its flavour, making it enjoyable. It’s rich in 100% vitamin E and Omega 3, vital for heart health, hair, and more. Don’t overlook this product if you're focused on hair health!
Read More
7
Enhances cardiovascular health
1 people found this helpful
Delicious oil! It is of superb quality. While I can't drink it straight, I add it to my salad for its rich aroma, which enhances the flavour! This oil is packed with Omega and nutritious ingredients, improving bodily functions. It normalises heart activity and addresses inflammation. I've noticed my hair is now shinier and more vibrant! I highly recommend it. ❤️
Read More
7
Skin healing effects
1 people found this helpful
I appreciate this product for treating red lines and skin cracks. The box quality is excellent, and while it has a slightly unpleasant smell, it doesn't matter when mixed. I completely recommend this product, as it helps reduce the appearance of wounds. The ingredients are of high quality and beneficial for hair and heart health.
Read More
Frequently Asked Questions
A heart attack, also known as myocardial infarction, occurs when blood flow to a part of the heart is blocked, often by a blood clot. This interruption can damage or destroy part of the heart muscle, leading to serious health complications or death if not treated promptly. Common symptoms include chest pain, shortness of breath, nausea, and lightheadedness. Risk factors include high blood pressure, high cholesterol, smoking, diabetes, and a sedentary lifestyle.
Preventing a heart attack largely revolves around maintaining a heart-healthy lifestyle. Regular exercise, a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, along with managing stress, can significantly lower the risk. Furthermore, understanding your personal risk factors and engaging with healthcare professionals for regular check-ups can be crucial in both prevention and early detection. If you suspect someone is having a heart attack, it's important to call emergency services immediately, as timely treatment is vital for survival and recovery.
Efa Omega 3 6 9 combinations refer to dietary supplements that provide a blend of essential fatty acids, specifically omega-3, omega-6, and omega-9 fatty acids. Omega-3 fatty acids, commonly found in fish oil and flaxseed, are known for their anti-inflammatory properties and heart health benefits. Omega-6 fatty acids are essential for brain function and are typically sourced from vegetable oils, while omega-9 acids, found in olive oil and certain nuts, support overall heart health by improving cholesterol levels.
Including a balanced ratio of these fatty acids in your diet can support various health functions, including cardiovascular health, cognitive performance, and skin health. Many people take Efa Omega 3 6 9 combinations to ensure they're getting a sufficient intake of these fatty acids, especially if their diet lacks fish or other rich sources. However, it is essential to consult with a healthcare provider before starting any new supplement, as the right balance for individual needs can vary significantly.
While Efa Omega 3 6 9 combinations are often marketed for their heart health benefits, it's crucial to approach this topic with a nuanced understanding. Omega-3 fatty acids, found in fish oil and certain plant oils, are well-researched for their cardiovascular benefits, including reducing inflammation and lowering triglyceride levels. Omega-6 fatty acids can also contribute to heart health when balanced with omega-3s, but excessive consumption may not provide the same benefits. Omega-9 fatty acids, typically found in olive oil, are beneficial as well, but they are not deemed essential since the body can produce them.
Although incorporating omega fatty acids into your diet can support heart health, they should not be viewed as a substitute for traditional heart disease treatments or preventive measures, such as a balanced diet, regular exercise, and routine medical check-ups. If you have concerns about heart disease or heart attacks, it's essential to consult with a healthcare provider for personalized advice and treatment options. In summary, while Efa Omega 3 6 9 combinations may play a supportive role in heart health, they are not a cure-all solution. Always prioritize a holistic approach in managing your cardiovascular health.
Recent research has explored several supplements and compounds with potential benefits in the context of heart attack recovery, providing insight into their efficacy. One notable study investigated TAPI-1, a protein delivered via neutrophil-mimicking nanoparticles, which showed promising results in reducing heart damage and improving function in rat models following a heart attack [1]. Additionally, innovative approaches using modified RNA in stem cells have demonstrated enhanced recovery by promoting blood flow and reducing cell death post-attack [6].
However, not all supplements correlate positively with heart health. A notable example is vitamin E; while some studies have linked higher consumption to reduced risks of cardiovascular events [8] and improved heart function [9], others have shown paradoxical results, suggesting that increased levels could elevate the risk of coronary artery disease [10]. Furthermore, a clinical trial indicated that while vitamin E might help mitigate inflammation after an attack, it does not significantly improve cardiac function [7]. This indicates the necessity for further research to clarify the complexities surrounding these supplements in heart attack management.
Based on user reviews, many individuals report a variety of improvements in their symptoms after using the product. For instance, one user noted that the oil provides exceptional moisturization benefits, which they described as deeply nourishing not just for the skin, but also for overall heart health Read Review. Another consumer highlighted its richness in vitamin E and Omega 3, which they believe is crucial for both hair vitality and heart functionality. They shared that the oil improved bodily functions and normalized heart activity while also addressing inflammation Read Review.
Additionally, users report favorable effects on the skin, with one reviewer stating they used the product to treat skin issues such as red lines and cracks. They observed a reduction in the appearance of wounds, attributing this improvement to the high-quality ingredients in the oil Read Review. Overall, while individual results may vary, these anecdotal experiences suggest that users have found benefits in both their skin condition and overall health when incorporating the oil into their routines.
Based on user reviews, many individuals have reported positive outcomes when combining this supplement, particularly heavy wheat germ oil, with other dietary components. One user emphasized the oil's exceptional quality and noted its high vitamin E and Omega 3 content, vital for promoting heart health and bodily functions. They specifically mentioned enjoying the product in salads, which not only masks its flavor but also enhances the overall taste while contributing to their diet Read Review.
Additionally, users have highlighted the oil's multifaceted benefits, noting improvements in heart activity and a reduction in inflammation when used in conjunction with other healthy foods. A user reported that adding the oil to their meals helped normalize heart functions, thereby demonstrating that this supplement can be effectively integrated into a broader health regimen Read Review. Such anecdotal experiences suggest that individuals are finding value in the synergistic effects of combining the oil with various dietary elements to support heart health.
9
Moisturises heart
Mrahha, it deeply moisturises the heart.
7
Enhances cardiovascular health
1 people found this helpful
Delicious oil! It is of superb quality. While I can't drink it straight, I add it to my salad for its rich aroma, which enhances the flavour! This oil is packed with Omega and nutritious ingredients, improving bodily functions. It normalises heart activity and addresses inflammation. I've noticed my hair is now shinier and more vibrant! I highly recommend it. ❤️
7
Skin healing effects
1 people found this helpful
I appreciate this product for treating red lines and skin cracks. The box quality is excellent, and while it has a slightly unpleasant smell, it doesn't matter when mixed. I completely recommend this product, as it helps reduce the appearance of wounds. The ingredients are of high quality and beneficial for hair and heart health.
9
Nutrient-rich oil
1 people found this helpful
The quality of heavy wheat germ oil is exceptional, offering numerous health benefits. Mixing it with salad masks its flavour, making it enjoyable. It’s rich in 100% vitamin E and Omega 3, vital for heart health, hair, and more. Don’t overlook this product if you're focused on hair health!
9
Nanoparticle delivery improves heart recovery
Targeted delivery of TAPI-1 via biomimetic nanoparticles ameliorates post-infarct left ventricle function and remodeling.
We explored the potential of TAPI-1, a protein that inhibits harmful enzymes, in treating heart damage after a heart attack, using a novel delivery method. To enhance its effectiveness, researchers created nanoparticles that mimic neutrophils, a type of immune cell that quickly appears in injured heart tissue.
These specialized nanoparticles were loaded with TAPI-1 and specifically designed to target inflamed areas of the heart in rats following a heart attack. By delivering TAPI-1 more precisely, we aimed to reduce heart injury and improve heart function.
Our results were promising—injecting TAPI-1 through these neutrophil-mimicking nanoparticles led to better heart performance and less scar tissue compared to standard TAPI-1 treatments. Not only did the targeted approach seem to optimize the protein's effects, but it also helped lessen the overall inflammation within the heart.
In summary, this study highlights a strategic advancement in delivering the TAPI-1 protein that could lead to more effective treatments for heart attack recovery, ultimately improving patient outcomes.
9
VEGFA, bFGF enhance heart recovery
Enhanced human adipose-derived stem cells with VEGFA and bFGF mRNA promote stable vascular regeneration and improve cardiac function following myocardial infarction.
We aimed to uncover how the proteins VEGFA and bFGF can support heart recovery following a heart attack, and we did this by enhancing human adipose-derived stem cells (hADSCs) with modified mRNA. These proteins are known to play a role in improving blood flow and reducing cell death, both vital for effective healing.
By modifying the hADSCs to overexpress these proteins, we sought to improve their ability to support the heart during such a critical time. Importantly, our approach involved using a new technique that enables the hADSCs to produce these growth factors in a timed, efficient manner. This modification not only led to better survival of the transplanted cells but also promoted stable formation of new blood vessels at the site of injury.
We observed that the infused hADSCs improved overall heart function and electrical activity, suggesting a robust response to the proteins we introduced. The results indicate that the combination of these engineered stem cells and the proteins could substantially enhance recovery after a heart attack, paving the way for new treatments for heart diseases caused by ischemia.
8
Vitamin E reduces heart attack risk
Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data.
We explored the effects of dietary vitamin E on heart attack and overall health by analyzing data from over 39,000 participants in the NHANES survey from 2003 to 2018. Our findings indicated that a higher intake of vitamin E was linked to a lower risk of cardiovascular disease and reduced all-cause mortality.
Specifically, those consuming more than 9.86 mg of vitamin E had significantly lower odds of developing cardiovascular issues, including heart attacks. However, the impact on cardiovascular mortality wasn't as strong. This suggests that while vitamin E-rich diets could enhance heart health, further research is necessary for clearer conclusions.
9
Hydrogel with vitamin E aids recovery
Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair.
We explored how an innovative hydrogel enhanced heart repair after a heart attack. This injectable hydrogel includes α-tocopherol, a form of vitamin E. In our study using a rabbit model, we implanted the hydrogel after inducing a heart attack.
Four weeks later, the results were promising. We noticed improved heart function and reduced damage to heart tissue. This suggests that the hydrogel, enriched with vitamin E, plays a vital role in helping the heart recover better after an injury.
2
Vitamin E links to heart risks
Circulating Vitamin E Levels and Risk of Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study.
We explored the relationship between vitamin E and heart attack risk through a two-sample mendelian randomization study. Using genetic variations from nearly 8,000 individuals of European descent, we dug into whether higher levels of vitamin E could protect against coronary artery disease (CAD) and myocardial infarction (MI).
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
7
Colchicine impact on heart health
Efficacy of Colchicine in Reducing NT-proBNP, Caspase-1, TGF-β, and Galectin-3 Expression and Improving Echocardiography Parameters in Acute Myocardial Infarction: A Multi-Center, Randomized, Placebo-Controlled, Double-Blinded Clinical Trial.
We conducted a double-blinded, placebo-controlled clinical trial to investigate how colchicine—a drug known for its anti-inflammatory properties—affects patients after an acute myocardial infarction (AMI), commonly known as a heart attack. Our study included 161 eligible participants from three hospitals in East Java, Indonesia, where they were randomly assigned to receive either colchicine or standard treatment over a 30-day period.
Throughout the trial, we measured key inflammatory markers and cardiac health indicators. While colchicine did lower NT-proBNP, a protein associated with heart failure, and also significantly reduced levels of Caspase-1, TGF-β, and Galectin-3—markers indicating inflammation and fibrosis—there was no notable improvement in echocardiography parameters measuring heart function.
This finding illustrates that while colchicine may help reduce certain inflammatory responses following a heart attack, it did not lead to measurable improvements in heart function as assessed through echocardiography. Thus, we conclude that the effects of colchicine could be beneficial for mitigating inflammation post-AMI, but it does not significantly enhance cardiac function in the short term.
References
Chen Q, Yu Y, Tong L, Weiss RM, Wei SG. Targeted delivery of TAPI-1 via biomimetic nanoparticles ameliorates post-infarct left ventricle function and remodeling. Cardiovasc Res. 2025. doi:10.1093/cvr/cvaf039
Wu H, Jiang X, Fan H, Li J, Li Y, et al. Inhibition of circALPK2 enhances proliferation and therapeutic potential of human pluripotent stem cell-derived cardiomyocytes in myocardial infarction. Stem Cell Res Ther. 2025;16:107. doi:10.1186/s13287-025-04230-8
Lai J, Li L, Liu J, Yan Q, Xu Z, et al. CELF1 Promotes Post-myocardial Infarction Cardiac Remodeling Via Suppression of FMO2. Cardiovasc Toxicol. 2025;25:441. doi:10.1007/s12012-024-09951-5
Stephan JK, Knerr T, Gu Z, Li H, Brittian KR, et al. Neutrophil-secreted CHI3L1 exacerbates cardiac dysfunction and inflammation after myocardial infarction. FASEB J. 2025;39:e70422. doi:10.1096/fj.202401654R
Tan X, Wang X, Xu S, Zeng Y, Zhang G, et al. Identification of Cardiometabolic Protein Biomarkers for Acute Myocardial Infarction Using Olink Proteomics. J Inflamm Res. 2025;18:2629. doi:10.2147/JIR.S495784
Li K, Luo R, Yu X, Dong W, Hao G, et al. Enhanced human adipose-derived stem cells with VEGFA and bFGF mRNA promote stable vascular regeneration and improve cardiac function following myocardial infarction. Clin Transl Med. 2025;15:e70250. doi:10.1002/ctm2.70250
Astiawati T, Rohman MS, Wihastuti T, Sujuti H, Endharti AT, et al. Efficacy of Colchicine in Reducing NT-proBNP, Caspase-1, TGF-β, and Galectin-3 Expression and Improving Echocardiography Parameters in Acute Myocardial Infarction: A Multi-Center, Randomized, Placebo-Controlled, Double-Blinded Clinical Trial. J Clin Med. 2025;14. doi:10.3390/jcm14041347
Zeng Q, Liao M, Li Y, She F, Zhang P. Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data. Int J Cardiol Cardiovasc Risk Prev. 2025;24:200340. doi:10.1016/j.ijcrp.2024.200340
Zhang F, Zhang Y, Qian S, Qian X, Jiao J, et al. Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair. ACS Nano. 2024;18:10216. doi:10.1021/acsnano.4c00509
Wang T, Xu L. Circulating Vitamin E Levels and Risk of Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study. Nutrients. 2019;11. doi:10.3390/nu11092153
Pongkan W, Takatori O, Ni Y, Xu L, Nagata N, et al. β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice. Mol Nutr Food Res. 2017;61. doi:10.1002/mnfr.201601077
Loffredo L, Perri L, Di Castelnuovo A, Iacoviello L, De Gaetano G, et al. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis. Nutr Metab Cardiovasc Dis. 2015;25:354. doi:10.1016/j.numecd.2015.01.008
Shukla SK, Sharma SB, Singh UR. Pre-treatment with α-tocopherol and Terminalia arjuna ameliorates, pro-inflammatory cytokines, cardiac and apoptotic markers in myocardial infracted rats. Redox Rep. 2015;20:49. doi:10.1179/1351000214Y.0000000104
Rodrigo R, Hasson D, Prieto JC, Dussaillant G, Ramos C, et al. The effectiveness of antioxidant vitamins C and E in reducing myocardial infarct size in patients subjected to percutaneous coronary angioplasty (PREVEC Trial): study protocol for a pilot randomized double-blind controlled trial. Trials. 2014;15:192. doi:10.1186/1745-6215-15-192
Vardi M, Blum S, Levy AP. Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus - natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature. Eur J Intern Med. 2012;23:628. doi:10.1016/j.ejim.2012.04.009
Rautiainen S, Akesson A, Levitan EB, Morgenstern R, Mittleman MA, et al. Multivitamin use and the risk of myocardial infarction: a population-based cohort of Swedish women. Am J Clin Nutr. 2010;92:1251. doi:10.3945/ajcn.2010.29371
Blum S, Vardi M, Brown JB, Russell A, Milman U, et al. Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype. Pharmacogenomics. 2010;11:675. doi:10.2217/pgs.10.17
Punithavathi VR, Prince PS. Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats. Life Sci. 2010;86:178. doi:10.1016/j.lfs.2009.11.021